Ai

Building a Scaffold-Split Random Forest QSAR Co-Scientist for EGFR Inhibitor Discovery Using ChEMBL, RDKit, SHAP, and BRICS

In this tutorial, we build an end-to-end autonomous AI co-scientist workflow for next-generation EGFR inhibitor discovery, focusing on the C797S osimertinib-resistance mutation in non-small cell lung cancer. We start by resolving the biological target through ChEMBL and UniProt, then mine curated EGFR IC50 bioactivity records and convert them into a clean pIC50 modeling dataset. We […]

Building a Scaffold-Split Random Forest QSAR Co-Scientist for EGFR Inhibitor Discovery Using ChEMBL, RDKit, SHAP, and BRICS Read More »

anthropic's new "j lens" reveals a silent workspace inside claude that mirrors a leading theory of consciousness

Anthropic’s new “J-lens” reveals a silent workspace inside Claude that mirrors a leading theory of consciousness

Anthropic, the artificial intelligence company, published a sweeping research paper on Sunday revealing that its Claude language models have spontaneously developed an internal structure that mirrors one of the most influential theories of how human consciousness works. The finding, which the company says has already begun reshaping how it monitors its AI systems for safety

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tencent's apache licensed hy3 takes on glm 5.2 at half the size — and wins everywhere except coding

Tencent’s Apache-licensed Hy3 takes on GLM-5.2 at half the size — and wins everywhere except coding

For the past year, the awkward secret of the open-weight model boom has been that many of the strongest Chinese releases were off-limits to a large slice of the enterprises most interested in them. License terms that excluded the European Union, the United Kingdom and South Korea meant legal teams killed deployments before engineering teams

Tencent’s Apache-licensed Hy3 takes on GLM-5.2 at half the size — and wins everywhere except coding Read More »

sakana ai launches sakana translate, a namazu powered japanese–english–chinese translation tool with translate, proofread, and ask modes

Sakana AI Launches Sakana Translate, a Namazu-Powered Japanese–English–Chinese Translation Tool With Translate, Proofread, and Ask Modes

Sakana AI has added a new feature called Sakana Translate to its chat service, Sakana Chat. It handles bidirectional translation across Japanese, English, and Chinese. The translation engine is Namazu, the company’s model series adapted for Japanese. Sakana Translate ships as a free web app. A single account unlocks all three of its modes. What

Sakana AI Launches Sakana Translate, a Namazu-Powered Japanese–English–Chinese Translation Tool With Translate, Proofread, and Ask Modes Read More »

Synthetic Sciences Releases OpenScience: An Open-Source, Model-Agnostic AI Workbench for Machine Learning, Biology, Physics, and Chemistry Research

Synthetic Sciences has released OpenScience, an open-source AI workbench for scientific research. It is licensed under Apache 2.0 and runs on your own infrastructure. The research team frames it as an open alternative to Anthropic’s Claude Science, launched in late June 2026. The pitch is direct. Scientific AI tooling should not be owned by one

Synthetic Sciences Releases OpenScience: An Open-Source, Model-Agnostic AI Workbench for Machine Learning, Biology, Physics, and Chemistry Research Read More »

Training Gemma-3 for Structured Mathematical Reasoning with Tunix GRPO, LoRA Adapters, and GSM8K Rewards

In this tutorial, we build an end-to-end GRPO training workflow that teaches Gemma-3 to reason through GSM8K math problems using Tunix, JAX, LoRA, and custom reward functions. We start by preparing the environment, authenticating with Hugging Face, loading the Gemma-3 model, and wrapping GSM8K examples into a prompt format that requires both structured reasoning and

Training Gemma-3 for Structured Mathematical Reasoning with Tunix GRPO, LoRA Adapters, and GSM8K Rewards Read More »

meituan releases longcat 2.0: a 1.6t parameter open moe model with native 1m context and longcat sparse attention

Meituan Releases LongCat-2.0: A 1.6T-Parameter Open MoE Model with Native 1M Context and LongCat Sparse Attention

Meituan has released LongCat-2.0, a large-scale Mixture-of-Experts (MoE) language model. It carries 1.6 trillion total parameters and activates about 48 billion per token. The model targets agentic coding: code understanding, generation, and execution inside agent workflows. Two facts stand out. First, LongCat-2.0 supports a native 1-million-token context window. Second, both training and serving ran entirely

Meituan Releases LongCat-2.0: A 1.6T-Parameter Open MoE Model with Native 1M Context and LongCat Sparse Attention Read More »

LlamaIndex ‘legal-kb’: Agentic Retrieval over Index v2 with retrieve, find, read, and grep Tools

LlamaIndex has published legal-kb, a public reference application on GitHub. It is described as a knowledge base for legal documents, powered by LlamaIndex Index v2 (the LlamaParse Platform). The project demonstrates a pattern the team calls a Retrieval Harness for agentic retrieval. The approach differs from single-shot retrieval. Instead of one embedding search per query,

LlamaIndex ‘legal-kb’: Agentic Retrieval over Index v2 with retrieve, find, read, and grep Tools Read More »

Structured PDF-to-JSON: A Guide to Open-Source Extraction Models in 2026

Most enterprise data still sits inside PDFs, scans, and slide decks. Large language models and agents cannot use that data until it becomes structured JSON. Open-source document extraction has become the standard way to do that conversion on your own hardware. Two different problems hide under the phrase ‘PDF to JSON.’ The first is schema-driven

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qwen’s former lead on what hybrid thinking got wrong — and why he now backs agents

Qwen’s Former Lead on What Hybrid Thinking Got Wrong — and Why He Now Backs Agents

Junyang Lin was the technical lead of Alibaba’s Qwen project. He announced he was stepping down on March 3, 2026. He now lists himself as an independent researcher on his personal site. In a talk titled ‘Qwen: Towards a Generalist Model / Agent,‘ he walks through the Qwen family. It ends on a single line:

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